解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::3,4-Methylenedioxymethamphetamine (MDMA; 'Ecstasy') is a psychostimulant drug producing heightened mood and facilitated social communication. In animal studies, MDMA effects are primarily mediated by serotonin (5-HT), but also by dopamine (DA) and possibly noradrenaline (NA). In humans, however, the neurochemical and ...
journal_title:Human brain mapping
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/hbm.1049
更新日期:2001-11-01 00:00:00
abstract::The practical use of realistic models in bioelectromagnetism is limited by the time-consuming amount of numerical calculations. We propose a method leading to much higher speed than currently available, and compatible with any kind of numerical methods (boundary elements (BEM), finite elements, finite differences). Il...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.1041
更新日期:2001-09-01 00:00:00
abstract::The present study investigates human visual processing of simple two-colour patterns using a delayed match to sample paradigm with positron emission tomography (PET). This study is unique in that we specifically designed the visual stimuli to be the same for both pattern and colour recognition with all patterns being ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:
更新日期:2001-08-01 00:00:00
abstract::A theoretical framework supporting experimental measures of dynamic properties of human EEG is proposed with emphasis on distinct alpha rhythms. Robust relationships between measured dynamics and cognitive or behavioral conditions are reviewed, and proposed physiological bases for EEG at cellular levels are considered...
journal_title:Human brain mapping
pub_type: 杂志文章,评审
doi:10.1002/hbm.1030
更新日期:2001-07-01 00:00:00
abstract::In this article we describe a new method, using SPM99, that searches explicitly for bilateral structural abnormalities. Children with bilateral pathology have a poorer prognosis than children with unilateral damage. After brain injury or disease in childhood, it is thought that rescue of function is only possible if t...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:
更新日期:2000-11-01 00:00:00
abstract::We present a novel, computerized method of examining cerebral cortical thickness. The normal cortex varies in thickness from 2 to 4 mm, reflecting the morphology of neuronal sublayers. Cortical pathologies often manifest abnormal variations in thickness, with examples of Alzheimer's disease and cortical dysplasia as t...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/1097-0193(200009)11:1<12::aid-hbm20>3.0.co
更新日期:2000-09-01 00:00:00
abstract::Active listening has been reported to elicit a different sensory response from passive listening and is generally observed as an increase in the magnitude of activation. Sensory activation differences may therefore be masked by the effect of attention. The present study measured activation induced by static and modula...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:
更新日期:2000-07-01 00:00:00
abstract::Although much has been learned about the functional organization of the human brain through lesion-deficit analysis, the variety of statistical and image-processing methods developed for this purpose precludes a closed-form analysis of the statistical power of these systems. Therefore, we developed a lesion-deficit si...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/(sici)1097-0193(200006)10:2<61::aid-hbm20>
更新日期:2000-06-01 00:00:00
abstract::This paper describes a Bayesian method for three-dimensional registration of brain images. A finite element approach is used to obtain a maximum a posteriori estimate of the deformation field at every voxel of a template volume. The priors used by the MAP estimate penalize unlikely deformations and enforce a continuou...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/(sici)1097-0193(200004)9:4<212::aid-hbm3>3
更新日期:2000-04-01 00:00:00
abstract::There are two basic types of photoreceptors in the retina: rods and cones. Using a single stimulus viewed at two different light levels, we tested whether input from rods and input from cones are topographically segregated at subsequent levels of human visual cortex. Here we show that rod-mediated visual input produce...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::We propose a hardware and software architecture to respond to crucial problems in the neuroimaging field: storage, retrieval, and processing of large datasets. The B-SPID project, here discussed, concerns the processing of neuroimages and attached components stored in an object-relational multimedia database managemen...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/(sici)1097-0193(1999)7:2<136::aid-hbm6>3.0
更新日期:1999-01-01 00:00:00
abstract::Functional magnetic resonance imaging (fMRI) and magnetoencephalography (MEG) were used to study the relationships between lateralized auditory perception in humans and the contralaterality of processing in auditory cortex. Subjects listened to rapidly presented streams of short FM-sweep tone bursts to detect infreque...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::The reproducibility of activation patterns in the whole brain obtained by functional magnetic resonance imaging (fMRI) experiments at 4 Tesla was studied with a simple finger-opposition task. Six subjects performed three runs in one session, and each run was analyzed separately with the t-test as a univariate method a...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/(sici)1097-0193(1999)7:4<267::aid-hbm5>3.0
更新日期:1999-01-01 00:00:00
abstract::We present an overview of the types of imaging experiments that can be performed on psychologically impaired patients. The critical observation from such studies is a differential pattern of activation in the patients and normals. Underactivity is interpretable only when the patients make normal responses. In this con...
journal_title:Human brain mapping
pub_type: 杂志文章,评审
doi:10.1002/(sici)1097-0193(1999)8:2/3<102::aid-hbm6>3
更新日期:1999-01-01 00:00:00
abstract::The use of functional magnetic resonance imaging (fMRI) to explore central auditory function may be compromised by the intense bursts of stray acoustic noise produced by the scanner whenever the magnetic resonance signal is read out. We present results evaluating the use of one method to reduce the effect of the scann...
journal_title:Human brain mapping
pub_type: 临床试验,杂志文章
doi:10.1002/(sici)1097-0193(1999)7:3<213::aid-hbm5>3.0
更新日期:1999-01-01 00:00:00
abstract::The neurons of the human cerebral cortex are arranged in a highly folded sheet, with the majority of the cortical surface area buried in folds. Cortical maps are typically arranged with a topography oriented parallel to the cortical surface. Despite this unambiguous sheetlike geometry, the most commonly used coordinat...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/(sici)1097-0193(1999)8:4<272::aid-hbm10>3.
更新日期:1999-01-01 00:00:00
abstract::Positron emission tomography (PET) was used to investigate the functional anatomy of the foveal fixation system in 10 subjects scanned under three different conditions: at rest (REST), during the fixation of a central point (FIX), and while fixating the same foveal target during the presentation of peripheral visual d...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/(sici)1097-0193(1999)8:1<28::aid-hbm3>3.0.
更新日期:1999-01-01 00:00:00
abstract::A method for representing the results of statistical EEG analysis in a visually comprehensive and concentrated way is presented. It consists of a combination of scattered data interpolation, texture mapping, and volume rendering techniques. First, starting with an EEG study of the proband in question, a smoothly inter...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::The registration of image volumes derived from different imaging modalities such as MRI, PET, SPECT, and CT has been described in numerous studies in which functional and morphological data are combined on the basis of macrostructural information. However, the exact topography of architectural details is defined by mi...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::Transcranial magnetic stimulation (TMS) during positron emission tomography (PET) is a novel technique for in vivo measurements of connectivity and excitability of the human cerebral cortex. Here we describe tools that allow investigators to position the stimulating coil over a target region and to verify the actual p...
journal_title:Human brain mapping
pub_type: 杂志文章,评审
doi:
更新日期:1998-01-01 00:00:00
abstract::Neuroimaging studies in humans have consistently found robust activation of frontal, parietal, and temporal regions during working memory tasks. Whether these activations represent functional networks segregated by perceptual domain is still at issue. Two functional magnetic resonance imaging experiments were conducte...
journal_title:Human brain mapping
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1998-01-01 00:00:00
abstract::In the present study, functional magnetic resonance imaging (fMRI) was used to examine pain perception in humans. Three types of noxious stimuli were presented: electric shock (20.8 mA, 2 Hz), heat (48 degrees C), and mechanical, as well as a control tactile stimulus. The significance of activation at the level of the...
journal_title:Human brain mapping
pub_type: 临床试验,杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::We present a method for registering a brain in the Talairach coordinate system that can be performed either "online," i.e., in real time while a subject is in a magnetic resonance scanner, or "offline" on a previously acquired three-dimensional (3D) data set. The method is applicable to functional magnetic resonance i...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0193(1997)5:1<58::AID-HBM6>3.0.
更新日期:1997-01-01 00:00:00
abstract::We describe a functional neuroanatomy approach that combines structural (MRI) and functional (PET) data at the individual level. For each subject MRI dataset, sulci are first localized using hemisphere surface rendering and sections and stored. Using these landmarks, the subject brain volume is then divided in 100 ana...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0193(1997)5:4<228::AID-HBM4>3.0
更新日期:1997-01-01 00:00:00
abstract::Brain activity was studied with fMRI and steady-state visual evoked potentials (SSVEPs) in separate sessions as subjects attended to letter sequences in either the right or left visual field. The two letter sequences were superimposed on small square backgrounds that flickered at 8.6 and 12.0 Hz, respectively, and eli...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0193(1997)5:4<287::AID-HBM14>3.
更新日期:1997-01-01 00:00:00
abstract::The human brain can be subdivided many ways depending upon the criteria used. One of the most basic approaches is to subdivide the cortical regions into functional units composed of the frontal, occipital, parietal, and temporal lobes. To date, the process of reliably extracting measurements of the human brain from MR...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0193(1997)5:5<355::AID-HBM4>3.0
更新日期:1997-01-01 00:00:00
abstract::Increased cerebral blood flow in the anterior cingulate cortex (ACC) has been noted in a range of cognitively demanding tasks studied with PET. A PET study of 10 normal males was carried out using the bolus H2(15)O intravenous injection technique to examine the effects of anticipation on blood flow to the ACC. In a se...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0193(1996)4:2<103::AID-HBM2>3.0
更新日期:1996-01-01 00:00:00
abstract::The Stroop interference test requires a person to respond to specific elements of a stimulus while suppressing a competing response. Previous positron emission tomography (PET) work has shown increased activity in the right anterior cingulate gyrus during the Stroop test. It is unclear, however, whether the anterior c...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.460010305
更新日期:1994-01-01 00:00:00